Seventeen Seasons and Counting

'Grey's Anatomy': This Is "Izzie", "Cristina" and More Today

When a show has been on the air for as long as Grey's Anatomy has, it is expected that not all the original cast members stick around. In fact, only three of the original cast members remain on the show.

The fictional series premiered in 2005 and focuses on those working at Seattle Grace Hospital. We experience their careers and personal lives while watching Grey's Anatomy. The show is the longest-running US primetime medical drama TV series and has earned many awards. To find out what some of the original cast members are doing now, please watch the video above.