Melissa has two younger siblings who are also actors! Her sister Sara Gilbert has become known for starring in The Conners as "Darlene Conner". Meanwhile, her brother Jonathan Gilbert only has a few acting credits, but appeared alongside Melissa in Little House on the Prairie, known for his role of "Willie Oleson".
Melissa Ellen Gilbert was born on May 8, 1964 in Los Angeles, California. She began her career as an actress when she was only a few years old, which is unsurprising seeing as her adoptive parents were both in the industry!