The 10 Most Beautiful Women of the 2000s: Ranked!

In the 2000s, several actresses made their big break and became stars who are now an integral part of Hollywood. Find out here which 10 of these women "Ranker" considers the most beautiful.

Angelina Jolie rounds out the top 10 most beautiful women. In the 2000s, she transformed from a Hollywood rebel into a character actress. In 2000, she won an Oscar for "Girl, Interrupted." As Lara Croft in “Tomb Raider” (2001), she became an action star. In 2005, she began a relationship with her ex-husband Brad Pitt, which captivated the media for years. Jolie became increasingly involved in humanitarian work and served as a UN Special Envoy. In 2014, she directed "Unbroken." In 2021, she made her Marvel debut in "Eternals." Most recently, she appeared on screen in 2025 for the film "Couture."

Ninth place goes to none other than Penélope Cruz. She took Hollywood by storm in the 2000s. In 2001, she wowed audiences in "Vanilla Sky" alongside Tom Cruise. In 2006, she shone in "Volver" directed by Pedro Almodóvar. In 2009, Cruz became the first Spanish woman to win an Oscar for “Vicky Cristina Barcelona.” To this day, she continues to shine on the big screen and always looks stunning. Her most recent film was “The Invite” in 2026.

Jessica Biel comes in at number eight. Justin Timberlake's wife became a teen idol in the 2000s thanks to "The Nanny." In 2003, she took a risk with "The Texas Chainsaw Massacre" to change her image. This was followed by leading roles in “Blade: Trinity” (2004) and “The Illusionist” (2006). Biel founded her own production company in 2014. In 2022, she enjoyed great success as both producer and lead actress in the series “Candy.” In 2023, she produced “Cruel Summer.” In 2025, she starred in the series “The Perfect Sister.”

Kate Beckinsale broke into Hollywood in 2001 with “Pearl Harbor.” She ranks 7th on the “Ranker” list. In 2003, Kate became an action star with “Underworld.” The franchise grossed over $500 million. At the same time, she demonstrated her acting talent in dramas such as “The Aviator” (2004). With her striking looks, she never fails to turn heads on the red carpet. “Wildcat” was her last project in 2025.

Sixth place goes to Salma Hayek. In the 2000s, she established herself as one of the most successful Latina actresses in Hollywood. In 2002, she received an Oscar nomination for "Frida." In 2007, she founded her own production company. She produced the hit series “Ugly Betty.” In 2021, Hayek joined the Marvel Universe in “Eternals.” In 2023, she shone in “Magic Mike’s Last Dance,” and in 2025, she starred in “Sacrifice.”

Megan Fox kicks off the Top 5. In 2007, she became the object of many people’s desires overnight thanks to “Transformers.” The film grossed over $700 million worldwide. In 2009, she shone in “Jennifer’s Body,” which didn’t achieve cult status until years later. After taking a break from her career, she made a comeback in 2020. In 2023, Fox published a collection of poems about toxic relationships. In 2025, she starred in “Five Nights at Freddy’s 2.”

Fourth place goes to Mila Kunis. The actress began her career in the late ’90s with “That ’70s Show.” In 2008, she made her big-screen debut with “Eternal Sunshine of the Spotless Mind.” Kunis established herself as a comedy talent. In 2010, she wowed critics in “Black Swan.” In 2023, Ashton Kutcher’s wife enjoyed success with the Netflix adaptation “Luckiest Girl Alive,” as well as in 2025 with the film “Wake Up Dead Man.”

Third place goes to her: Natalie Portman demonstrated her versatility in the 2000s. In 2004, she gave a brilliant performance in "Closer," for which she received an Oscar nomination. At the same time, she graduated from Harvard with a degree in psychology in 2003. In 2010, she won an Oscar for “Black Swan.” Portman is a strong advocate for women’s rights and co-founded the “Time’s Up” movement in 2018. In 2026, she caused a stir with the film “The Gallerist.”

Scarlett Johansson takes second place. The beautiful blonde had her big breakthrough in 2003 with "Lost in Translation." The film earned her a BAFTA Award. In 2010, she joined the Marvel Universe as “Black Widow.” Johansson has become one of the highest-paid actresses in the world. She was last seen in “Jurassic World: Resurgence” in 2025.