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  3. 'Friends': The Most Famous Celebrity Guest-Stars

'Friends': The Most Famous Celebrity Guest-Stars

Allvipp Newsroom / October 22, 2025 - 10:00 pm

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Pinterest These Movies Are Based On Books
(© Getty Images)

Jeff Goldblum

Jeff Goldblum plays the role of legendary director "Leonard Hayes" in the season 9 episode "The One with the Mugging". "Joey" nails an audition he was offered by "Hayes" due to being tortured by a full bladder during his performance. He ends up relieving himself on the poor director...

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Pinterest Julia Roberts beim Special Screening des Kinofilms Leave the World Behind im Curzon Mayfair Cinema. Lonodn, 29.11.2023 *
(© IMAGO/Future Image)

Julia Roberts

Julia Roberts has an epic cameo in the classic sitcom! She plays the role of "Susie Moss," a girl "Chandler" used to tease back in high school. The two end up going on a date. At some point during the evening, "Susie" tells "Chandler" to put on her panties, which he thought was a kink... Turns out it was purely out of revenge!

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Pinterest Chrysalis' 5th Annual Butterfly Ball
(© 2006 Getty Images)

Charlie Sheen

Charlie Sheen plays "Phoebe's" long-lost lover who comes to visit her for two weeks. He wasn't even phased by the slightest after he found out our lovely protagonist had the chicken pox. The two still enjoyed their time together anyway...

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Pinterest Christina Applegate Reveals She Has Multiple Sclerosis Twitter announcement update today 2021 news
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Christina Applegate

That's right! Christina Applegate appeared in two episodes of 'Friends'. She plays "Amy Green," one of "Rachel's" spoiled sisters. Her character is very known for the scene where she takes her niece "Emma" to get her ears pierced without the consent of her parents. In her defense, she thought she was doing something nice! Anyway, Applegate did end up winning an Emmy for her performance!

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Pinterest 2022 ABC Disney Upfront
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Danny DeVito

Ok... This one really took us by surprise! Danny DeVito played a somewhat depressed stripper in an episode of 'Friends'. He is hired for "Phoebe's" bachelorette party, but, of course, it wasn't exactly what the girls were expecting...

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Pinterest RECORD DATE NOT STATED George Clooney at arrivals, THE BOYS IN THE BOAT Screening, MoMA Museum of Modern Art, New York,
(© IMAGO/Everett Collection)

George Clooney

After his role in 'E.R'. ended, Clooney was quickly able to find a guest role in the popular sitcom. He played the role of a dreamy doctor alongside fellow cast member Noah Wyle. What else did you think he was going to play?

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Pinterest Some Like It Hot Broadway Opening John Stamos attends the Some Like it Hot Broadway Opening on December 11, 2022 at The
(© IMAGO/Avalon.red)

John Stamos

Desperate for children, Chandler invites over a co-worker to dinner, who is played by John Stamos. Throughout the course of the evening, he is asked several personal health and family history questions by both "Monica" and "Chandler".

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Pinterest September 5, 2024, Toronto, On, Canada: Ben Stiller Is photographed as they arrive for the premiere of öÄòNutcrackersöÄ
(© IMAGO/ZUMA Press)

Ben Stiller

Ben Stiller played one of "Rachel's" dates in the episode, 'The One With The Screamer,' who hilariously yells at everybody and anything that bothers him. A very unusual role indeed...

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Pinterest Leah Remini
(© Getty Images)

Leah Remini

During the birth of "Ross's" son "Ben," everybody is seen gathering around and awaiting the bundle of joy. "Joey," on the other hand, is found helping another pregnant woman, played by Leah Remini, who was going to give birth seemingly alone...

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Pinterest Bruce Willis' wife releases emotional video
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Bruce Willis

Bruce Willis played the role of "Paul Stevens" in three seasons and 6 episodes of Friends. He is the father of "Ross's" young girlfriend and even starts dating "Rachel" at some point during season 6. You can imagine how awkward that was... Bruce did end up winning an Emmy for his guest role though...

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Friends was one of those shows that gained a huge fan base both during its 10-year run and after! 

'Friends': The Best Celebrity Guest-Stars

Due to its huge budget and wide audience appeal, the show was able to get quite a few very famous guest stars which really solidified the show's status! Let's take a look at some of the most memorable! 

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