11 / 12
"Marge" and "Homer Simpson" are one of those TV duos that never get old! What would the dim-witted "Homer" be without his patient wife, "Marge"?
12 / 12
Another great on-screen friendship was between "Joey" (Matt LeBlanc) and "Chandler" (Matthew Perry) in the sitcom Friends. The combination of the somewhat naive "Joey" and the sarcastic "Chandler" made the series a smash hit. If it wasn't for "Monica" (Courteney Cox), the two would have never even met!