Misery star Kathy Bates got creepy once more in Two and a Half Men season 9. "Alan" suffers a minor heart attack in episode "Why We Gave Up Women," after which he's visited by the "Ghost of Charlie Harper" — portrayed by Bates. For the role, the actress even earned an Emmy win for Outstanding Guest Actress in a Comedy Series.

Fans often name Jon Lovitz's role as one of Two and a Half Men's finest guest appearances. He played "Archie Baldwin," the enemy of "Charlie Harper," in season 3. A rival ad jingle writer, "Archie" always tops "Charlie" at the Jingle awards — and Lovitz even delivered a full, over-the-top performance number in the episode "The Unfortunate Little Schnauser."