Grey's Anatomy is known not just for its intense storylines, but also for the romances that develop between its characters. Over the years, the hit medical drama has featured many different pairings. While some were short-lived flings, there were relationships that ended in tragedy, and others that have stood the test of time.
From "MerDer" to "Slexie," and "Calzona" to "Schmico," we've gone and rounded up several of the most iconic relationships in Grey's Anatomy history. Click through the slides to find out more about the show's best couples!
Grey's Anatomy: The Most Beautiful Couples On The Series
"Meredith Grey" and "Derek Shepherd"
"Meredith" and "Derek" remain one of Grey's Anatomy's most iconic couples! Given the relationship nickname "MerDer" by fans, their love story sadly had a tragic ending when "Derek" was killed in a fatal car crash in season 11. However, "Meredith" saw visions of her former lover as she experienced coronavirus-induced hallucinations in season 17, suggesting that while "Derek" might be dead, their love will never be.
"Owen Hunt" and "Cristina Yang"
"Owen" and "Cristina's" relationship started out beautifully, but certainly had its highs and lows over the years! The two doctors first made things romantic in season 5, and married in season 7. Even after "Owen" cheated on "Cristina," and the couple remained in love, lasting until "Cristina" moved to Switzerland for work.